The Association between the First Cry and Clinical Outcomes in CDH Neonates: A Retrospective Study

Congenital diaphragmatic hernia (CDH) is a life-threatening condition characterized by the herniation of abdominal organs into thorax, resulting in hypoplastic lungs and pulmonary hypertension. The impact first cry, crucial event for lung transition during birth, on CDH patients remains unclear. This study investigated cry birth patient survival, along with other prognosis factors. A multi-institutional retrospective assessed characteristics survival rates analyzing factors including disease severity, weight, Apgar scores, oxygenation index (OI) surgical closure. Among study, positive was linked to 100% regardless severity (p < 0.001). Notably, presence did not significantly affect worse prognostic factors, such as low weight (<2500 g), high scores (1 min ≤ 4), best OI within 24 h after (≥8), or those who underwent patch Furthermore, no significant association found between use inhaled nitric oxide (iNO) extracorporeal membrane (ECMO). In conclusion, this suggests that may have negative could potentially effect.